Substance
ID:449357
Names and Identifiers
IUPAC name
7-methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one
IUPAC Traditional name
7-methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one
Synonyms
7-Methoxy-8-prenylcoumarinOsthol
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
Modulates TRH-evoked responses by interacting with the TRH receptor
Calcium blocking
Product Information
Application(s)
Analeptic
Biological Source
Isol. from Imperatoria ostruthium, Choisya spp., Seseli sibiricum, Prangos bucharica and Peucedanum hispanicum
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Murray, R.D.H. et al., The Natural Coumarins, J. Wiley, 1982, (occur)
• Bandopadhyay, M. et al., Indian J. Chem., 1974, 12, 23, (synth)
• Hollis, A.F. et al., Aust. J. Chem., 1961, 14, 101, (Osthol hydrochloride)
• Cai, J.-N. et al., J. Nat. Prod., 2000, 63, 485-488, (Osthol hydrate)
• Kumar, R. et al., Phytochemistry, 1978, 17, 2111, (Osthol)
• Kapoor, S.K. et al., Phytochemistry, 1968, 7, 147, (Osthol)
• Raj, K. et al., Indian J. Chem., Sect. B, 1976, 14, 332, (synth)
• Danchul, T.Y. et al., Khim. Prir. Soedin., 1977, 13, 575; Chem. Nat. Compd. (Engl. Transl.), 1977, 13, 479, (Osthol)
• Murray, R.D.H. et al., Tetrahedron, 1971, 27, 1247, (synth)
• Fujioka, T. et al., Chem. Pharm. Bull., 1999, 47, 96-100, (Osthol, pmr, cmr)