Substance
ID:449351
Names and Identifiers
IUPAC name
1,8-dihydroxy-3-methyl-9,10-dihydroanthracene-9,10-dione
Synonyms
Chrysophanic acid3-MethylchrysazinChrysophanolArchininRumicinRheic acid
IUPAC Traditional name
1,8-dihydroxy-3-methyl-9,10-dihydroanthracene-9,10-dione
Registration numbers
CAS Number
Properties
Product Information
Biological Source
Constit. of Cassia, Rumex, Rheum, Asphodelus and Muehlenbeckia spp., etc.
Also isol. from Monilinia fructicola.
V. widely distributed
Application(s)
Antimicrobial
Cathartic agent
Pharmacology Properties
Mechanism of Action
Inhibitor of phosphoinositide- 3-kinase (PI3K)/AKT
Monoamine oxidase inhibitor
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 88A, (ir)
• Labadie, R.P., Pharm. Weekbl., 1972, 107, 535, (occur)
• Rizk, A.M. et al., Phytochemistry, 1972, 11, 2122, (deriv)
• King, F.E. et al., J.C.S., 1952, 4580, (synth)
• Bloom, H. et al., J.C.S., 1959, 178, (ir)
• Karrer, W. et al., Konstitution und Vorkommen der Organischen Pflanzenstoffe, 2nd edn., Birkhuser Verlag, Basel, 1972, no. 1254, (occur)
• Thomson, W.H., Naturally Occurring Quinones, Recent Advances, Chapman and Hall, 1987, (occur)
• Schripsema, J. et al., Phytochemistry, 1996, 42, 177, (pmr, struct)
• Schmidt, R.R. et al., Synthesis, 1994, 255, (synth, pmr)
• Ahmed, S.A. et al., Chem. Comm., 1987, 883, (synth)
• Sassa, T. et al., Agric. Biol. Chem., 1991, 55, 95, (isol)
• Banville, J. et al., Can. J. Chem., 1974, 52, 80, (synth, uv, pmr)
• Harris, T.M. et al., J.A.C.S., 1976, 98, 6065, (synth)
• Kelly, T.R. et al., J.O.C., 1983, 48, 3573, (isol)
• Anderson, J.A. et al., Phytochemistry, 1986, 25, 103, (biosynth)
• Danielsen, K. et al., Magn. Reson. Chem., 1992, 30, 359, (pmr, cmr)
• Kraus, G.A. et al., J.O.C., 1983, 48, 3439, (synth)