Substance

ID:449318

Names and Identifiers
IUPAC name
7,8-dimethoxy-11-methyl-17,19-dioxa-11-azatetracyclo[12.7.0.04,9.016,20]henicosa-1(21),4(9),5,7,14,16(20)-hexaen-2-one
Synonyms
Gamma-Homochelidonine; Beta-HomochelidonineAlpha-FagarineAllocryptopine
IUPAC Traditional name
7,8-dimethoxy-11-methyl-17,19-dioxa-11-azatetracyclo[12.7.0.04,9.016,20]henicosa-1(21),4(9),5,7,14,16(20)-hexaen-2-one
Registration numbers
CAS Number
485-91-6
Properties
Product Information
Application(s)
Antiarrhythmic
Antihypertensive agent
Muscle relaxant
Respiratory stimulant
Cardiac inhibitor
Biological Source
Alkaloid from a wide variety of genera in the Fumariaceae ( Corydalis, Dactylicapnos ), Papaveraceae ( Argemone, Bocconia, Eschscholtzia, Glaucium, Hunnemannia, Hylomecon, Macleaya, Meconopsis, Papaver, Sanguinaria,
Pharmacology Properties
Mechanism of Action
Potassium outward current inducer
Molecule Details
No Data Available
Click here to submit data
Molecular Spectra
No Data Available
Click here to submit data
References
• Hruban, L. et al., Coll. Czech. Chem. Comm., 1967, 32, 3414, (uv)
• Dolejs, L. et al., Coll. Czech. Chem. Comm., 1964, 29, 2479, (ms)
• Battersby, A.R. et al., J.C.S. Perkin 1, 1975, 1147, (biosynth)
• Redemann, C.E. et al., J.A.C.S., 1949, 71, 1030, (uv, struct)
• Sakai, T. et al., Acta Cryst. C, 1988, 44, 838, (cryst struct)
• Deulofeu, V. et al., J.O.C., 1947, 12, 217, (struct)
• Ma, J.C.N. et al., Can. J. Chem., 1965, 43, 1849, (pmr)
• Haworth, R.D. et al., J.C.S., 1926, 445, (synth)
• Teitel, S. et al., Helv. Chim. Acta, 1973, 56, 553, (synth)
• Nakashima, T.T. et al., Org. Magn. Reson., 1973, 5, 9, (cmr)
• Iwasa, K. et al., J.O.C., 1982, 47, 4275, (pmr, cmr)
• Hanaoka, M. et al., Heterocycles, 1976, 4, 1685, (synth)
• Marek, J. et al., Coll. Czech. Chem. Comm., 1998, 63, 416-424, (cryst struct)
Navigation