Substance
ID:449303
Names and Identifiers
Synonyms
InosineHypoxanthine ribosideInosieOxiamineTrophicardylCarnineHypoxanthosine
IUPAC name
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
IUPAC Traditional name
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Used to treat cardiac disorders
Cardiotonic
Biological Source
Prod. by microorganisms, e.g. Bacillus subtilis, E. coli, Saccharomyces cerevisiae, Fusarium spp.
Pharmacology Properties
Mechanism of Action
Activates cellular functions by base pairs with Adenine HFN72-P, Cytosine HDR44-O or Uracil BTP40-U
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
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• Campoli-Richards, D.M. et al., Drugs, 1986, 32, 383, (rev, Inosine pranobex)
• Chenon, M.T. et al., J.A.C.S., 1975, 97, 4627, (cmr)
• Hawkes, G.E. et al., J.C.S. Perkin 2, 1977, 1268, (N-15 nmr)
• Westhof, E. et al., Z. Naturforsch., C, 1975, 30, 131, (pmr)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, IDE000
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 712B, (ir)
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• Ger. Pat., 1972, 2038262; CA, 76, 99993e, (synth)
• Yamazaki, A. et al., J. Het. Chem., 1978, 15, 353, (rev, synth)
• Kinichi, I. et al., Chem. Pharm. Bull., 1966, 14, 1377, (synth)
• Munns, A.R.I. et al., Acta Cryst. B, 1970, 26, 1114, (cryst struct)
• De Simone, C. et al., Int. J. Immunopharmacol., 1991, 13, 19, (rev, Inosine pranobex)
• Hall, R.H., Biochem. Biophys. Res. Commun., 1963, 13, 394, (isol, deriv)
• Japan. Pat., 1968, 68 13 215; CA, 70, 47808, (synth, isopropylidene)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 215C, (nmr)
• Aviado, D.M., J. Pharmacol., 1983, 14, 47, (rev, pharmacol)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 548; 1379