Substance
ID:449280
Names and Identifiers
IUPAC name
3-(2-methoxyethyl) 5-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Synonyms
NimodipineAdmonNimotopPeriplumKenesilCalnit
IUPAC Traditional name
3-(2-methoxyethyl) 5-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Cerebral vasodilator
Pharmacology Properties
Mechanism of Action
Calcium channel blockader
Nimodipine binds specifically to L-type voltage-gated calcium channels
Blocks intracellular influx of calcium that is thought to be a central to ischaemic neuronal damage.
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
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• Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 8483, (synonyms)
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• Nimodipine, (Eds. Scriabine, A. et al), Springer-Verlag, 1991, (book)
• Wadworth, A.N. et al., Drugs Aging, 1992, 2, 262, (rev)