Substance
ID:449272
Names and Identifiers
Synonyms
OlzapinZyprexaZolafrenZalastaOlanzapineZyprexa Zydis
IUPAC name
5-methyl-8-(4-methylpiperazin-1-yl)-4-thia-2,9-diazatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),5,8,10,12-hexaene
IUPAC Traditional name
5-methyl-8-(4-methylpiperazin-1-yl)-4-thia-2,9-diazatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),5,8,10,12-hexaene
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Used in the treatment of schizophrenia and bipolar disorder
Antipsychotic agent
Pharmacology Properties
Mechanism of Action
5HT(2) and dopamine D2 receptor antagonist
Molecule Details
No Data Available
Click here to submit data
Molecular Spectra
No Data Available
Click here to submit data
References
• Bhana, N. et al., Drugs, 2001, 61, 111-161, (rev)
• Fulle, R.W. et al., Res. Commun. Chem. Pathol. Pharmacol., 1992, 77, 87, (pharmacol)
• Fulton, B. et al., Drugs, 1997, 53, 281-298, (rev)
• Eur. Pat., 1991, Lilly, 454 436; CA, 116, 83703u, (synth, pharmacol)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 683
• Moore, N.A. et al., J. Pharmacol. Exp. Ther., 1992, 262, 545, (pharmacol)