Substance
ID:449236
Names and Identifiers
IUPAC Traditional name
sodium (2R)-2-(4-{[(1S)-2-oxocyclopentyl]methyl}phenyl)propanoate
IUPAC name
sodium (2R)-2-(4-{[(1S)-2-oxocyclopentyl]methyl}phenyl)propanoate
Synonyms
Loxoprofen SodiumLoxonin
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
Works by reducing the synthesis of prostaglandins from arachidonic acid
Non-selective cyclooxygenase inhibitor
Product Information
Application(s)
Non-steroidal antiinflammatory agent
Analgesic
Salt Data
Na+
Molecule Details
No Data Available
Click here to submit data
Molecular Spectra
No Data Available
Click here to submit data
References
• Hata, T. et al., Bull. Chem. Soc. Jpn., 1987, 60, 3535, (cryst struct)
• Naganuma, H. et al., J. Chromatogr., 1990, 530, 387, (hplc)
• Watanabe, T. et al., J. Toxicol. Clin. Toxicol., 1993, 31, 333, (tox)
• Sugimoto, M. et al., Biochem. Pharmacol., 1991, 42, 2363, (pharmacol)
• Takasaki, W. et al., Chirality, 1992, 4, 308, (metab)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 22
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, LII300
• Terada, A. et al., J. Med. Chem., 1984, 27, 212, (synth)
• Ger. Pat., 1978, Sankyo, 2 814 556; CA, 90, 22616r, (synth, pharmacol)
• Tanaka, Y. et al., Chem. Pharm. Bull., 1983, 31, 3656, (metab)
• Toshimasa, T. et al., J. Chromatogr., 1992, 627, 75, (hplc)