Substance
ID:449232
Names and Identifiers
Synonyms
KetasIbudilast
IUPAC name
2-methyl-1-[2-(propan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one
IUPAC Traditional name
2-methyl-1-[2-(propan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Antiallergic
Cerebral vasodilator
Bronchodilator
Neuroprotective
Pharmacology Properties
Mechanism of Action
Bronchodilator
Lowers Ca 2+ deposition in soft tissues
Phosphodiesterase inhibitor
Vasodilator
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Yasui, M. et al., J. Int. Med. Res., 1990, 18, 415, (pharmacol)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 1140
• Nagai, H. et al., Jpn. J. Pharmacol., 1983, 33, 1215, (pharmacol)
• Izumi, Y. et al., Arzneim.-Forsch., 1990, 40, 1300
• Ohashi, M. et al., Int. Arch. Allergy Appl. Immunol., 1993, 101, 288, (pharmacol)
• Souness, J.E. et al., Br. J. Pharmacol., 1994, 111, 1081, (pharmacol)
• Japan. Pat., 1977, Kyorin Pharm, 77 14 799; CA, 87, 53282w, (synth, pharmacol)
• Ger. Pat., 1973, Kyorin Pharm, 2 315 801; CA, 80, 14923s, (synth)
• Mue, S. et al., Arch. Int. Pharmacodyn. Ther., 1986, 283, 153, (pharmacol)