Substance
ID:449224
Names and Identifiers
IUPAC name
2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
Synonyms
CiprolLipanorCiprofibrate
IUPAC Traditional name
2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Effective in type Iia, Iib, III and IV hyperlipoproteinaemias and increases high-density lipoprotein
Hypolipidaemic agent
Pharmacology Properties
Mechanism of Action
Agonist of the PPARalpha receptor in muscle, liver, and other tissues
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Martindale, The Extra Pharmacopoeia, 31st edn., Pharmaceutical Press, 1996, 1304
• Gibson, G. et al., Peroxisomes: Biology and Importance in Toxicology and Medicine, Taylor and Francis, London, 1993, (rev)
• Chapman, M.J. et al., Atherosclerosis (Amsterdam), 1996, 124; S83, (pharmacol, use)
• Beyer, K.H. et al., Arch. Pharm. (Weinheim, Ger.), 1982, 315, 1049, (metab)
• Masnatta, L.D. et al., J. Chromatogr., B: Biomed. Appl., 1996, 687, 437, (hplc)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CMS210
• Arnold, A. et al., J. Pharm. Sci., 1979, 68, 1557, (props)
• Fr. Pat., 1974, Sterling Drug, 2 197 586; CA, 82, 43059m, (synth, pharmacol)