Substance
ID:449217
Names and Identifiers
Synonyms
ZometaZoledronic Acid
IUPAC name
[1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl]phosphonic acid
IUPAC Traditional name
[1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl]phosphonic acid
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Prevents skeletal fractures in patients with multiple myeloma and prostate cancer
Pharmacology Properties
Mechanism of Action
Human gamma-lambda T cells activator
Bone resorption inhibitor
Calcium regulator
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Dunford, J.E. et al., J. Pharmacol. Exp. Ther., 2001, 296, 235-242, (pharmacol)
• Berenson, J.R. et al., Cancer (Philadelphia), 2001, 91, 144-154, (pharmacol)
• Green, J.R. et al., J. Bone Min. Res., 1994, 9, 745, (pharmacol)
• U.S. Pat., 1990, Ciba-Geigy, 4 939 130; CA, 114, 62355a, (synth, pharmacol)
• Cheer, S.M. et al., Drugs, 2001, 61, 799-805, (rev)
• Sorbera, L.A. et al., Drugs of the Future, 2000, 25, 259-268, (rev)