Substance
ID:449208
Names and Identifiers
IUPAC name
2-(4-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}phenyl)benzoic acid
Synonyms
MicardisPritorKinzalTelmaTeleact DTelmisartan
IUPAC Traditional name
2-(4-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}phenyl)benzoic acid
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Antihypertensive agent
Pharmacology Properties
Mechanism of Action
Angiotensin II (AT 1 ) receptor antagonist
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Wienen, W. et al., Br. J. Pharmacol., 1993, 110, 245, (pharmacol)
• Su, C.A.P.F. et al., Clin. Pharmacol. Ther. (St. Louis), 1994, 55, 205, (pharmacol)
• Bhm, M. et al., J. Hypertens., 1995, 13, 891, (pharmacol)
• van Meel, J.C.A. et al., Arzneim.-Forsch., 1996, 46, 755, (pharmacol)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 951
• McClellan, K.J. et al., Drugs, 1998, 56, 1039-1044, (rev)
• Ries, U.J. et al., J. Med. Chem., 1993, 36, 4040, (synth, pmr, pharmacol)
• Eur. Pat., 1992, Thomae, 502 314; CA, 117, 251352v, (synth, pharmacol)
• Sharpe, M. et al., Drugs, 2001, 61, 1501-1529, (rev)
• Gavras, I. et al., Cardiovasc. Rev. Rep., 2000, 21, 76