Substance
ID:449192
Names and Identifiers
IUPAC name
2-ethoxy-4-({[(1S)-3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl]carbamoyl}methyl)benzoic acid
Synonyms
PrandinNovoNormRepaglinide
IUPAC Traditional name
2-ethoxy-4-({[(1S)-3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl]carbamoyl}methyl)benzoic acid
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Antihyperglycaemic agent used in the treatment of type II diabetes
Pharmacology Properties
Mechanism of Action
Stimulating the release of insulin from the pancreas by closing ATP-dependent potassium channels in the membrane of the beta cells
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Ger. Pat., 1987, Thomae, 3 522 604; CA, 106, 196260j, (synth)
• Eur. Pat., 1989, 147 850; CA, 104, 5651p
• Verspohl, E.J. et al., J. Pharm. Pharmacol., 1990, 42, 230, (pharmacol)
• Wolffenbuttel, B.H.R. et al., Eur. J. Clin. Pharmacol., 1993, 45, 113, (use)
• Pat. Coop. Treaty (WIPO), 1993, Thomae, 93 00 337; CA, 118, 254759q, (synth, isomers)