Substance
ID:449177
Names and Identifiers
Synonyms
PatadayPatanaseOpatanolOlopatadine HydrochloridePatanol SPatanol
IUPAC Traditional name
2-[(2Z)-2-[3-(dimethylamino)propylidene]-9-oxatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-5-yl]acetic acid hydrochloride
IUPAC name
2-[(2Z)-2-[3-(dimethylamino)propylidene]-9-oxatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-5-yl]acetic acid hydrochloride
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
Mediator release inhibitor
Histamine H1-receptor antagonist,
Product Information
Application(s)
Antiallergic agent
Used in the treatment of allergic rhinitis, urticaria, allergic conjunctivitis and asthma
Salt Data
HCl
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Ikemura, T. et al., Int. Arch. Allergy Appl. Immunol., 1996, 110, 57; 64, (pharmacol)
• Eur. Pat., 1987, Kyowa Hakko Kogyo, 235 796; CA, 108, 167330, (synth, pharmacol)
• Berdy, G.J. et al., Clin. Ther., 2000, 22, 826-833; 2001, 23, 1272-1280, (pharmacol)
• Ikeda, K. et al., Int. Arch. Allergy Appl. Immunol., 1995, 106, 157, (pharmacol)
• Oshima, E. et al., J. Med. Chem., 1992, 35, 2074, (synth, cryst struct, pharmacol)
• Sharif, N.A. et al., J. Pharmacol. Exp. Ther., 1996, 278, 1252, (pharmacol)