Substance
ID:449176
Names and Identifiers
IUPAC name
(5-methyl-2-oxo-2H-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazole-5-carboxylate
Synonyms
OlmetecBenicarOlmesartan
IUPAC Traditional name
(5-methyl-2-oxo-2H-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazole-5-carboxylate
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
Block the binding of angiotension II to the AT1 receptors in vascular muscle
Prodrug-type angiotensin II receptor antagonist
Angiotensin II receptor antagonists
Product Information
Application(s)
Antihypertensive agent
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Eur. Pat., 1992, Sankyo, 503 785; CA, 118, 22240k, (CS 866, RNH 6270, synth, pharmacol)
• Mizuno, M. et al., Eur. J. Pharmacol., 1995, 285, 181-188, (pharmacol, CS 866, RNH 6270)
• Yanagisawa, H. et al., J. Med. Chem., 1996, 39, 323-328, (synth, CS 866, RNH 6270, pmr, ir, pharmacol)