Substance
ID:449151
Names and Identifiers
IUPAC name
4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid
Synonyms
FursemideLasixFrumaxDryptalRusydeFrusemideDiurapidFrusidFrusolTenkafruseFroop
IUPAC Traditional name
4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
Inhibitor of carbonic anhydrase,
subtype-specific blocker of GABA-A receptors
Product Information
Application(s)
Used for treatment of cirrhotic patients with ascites.
Antihypertensive
Used in conjunction with Spironolactone HJR81-N for prophylaxis of hypokalaemia and hepatic encephalopathy or in treatment of hyperaldosteronism
Diuretic
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
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• Lamotte, J. et al., Acta Cryst. B, 1978, 34, 1657, (cryst struct)
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• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 41C, (nmr)
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 591A, (ir)
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• Aspects of Diuretic Therapy with Furosemide: an Update, Wells Medical, 1993, (book)
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