Substance

ID:449142

Names and Identifiers
IUPAC Traditional name
4-({2-butyl-5-[(1E)-2-carboxy-2-(thiophen-2-ylmethyl)eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid
IUPAC name
4-({2-butyl-5-[(1E)-2-carboxy-2-(thiophen-2-ylmethyl)eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid
Synonyms
EprosartanTeveten
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Antihypertensive agent
Pharmacology Properties
Mechanism of Action
Angiotensin II AT 1 -receptor antagonist
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Eur. Pat., 1990, SmithKline Beckman, 403 159; CA, 114, 207258h, (synth, pharmacol)
• Weinstock, J. et al., J. Med. Chem., 1991, 34, 1514; 1993, 36, 1880, (synth, pharmacol, pmr)
• Plosker, G.L. et al., Drugs, 2000, 60, 177-201, (rev)
• Edwards, R.M. et al., J. Pharmacol. Exp. Ther., 1992, 260, 175, (pharmacol)
• McLellan, K.J. et al., Drugs, 1998, 55, 713-718, (rev)
• Wittenberger, S.J. et al., Synth. Commun., 1993, 23, 3231, (synth, pmr, cmr)