Substance
ID:449133
Names and Identifiers
IUPAC name
1-cyclopropyl-6-fluoro-7-[(1R,4R)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; methanesulfonic acid
IUPAC Traditional name
1-cyclopropyl-6-fluoro-7-[(1R,4R)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; methanesulfonic acid
Synonyms
MonomethanesulfonateDanofloxacin Mesylate
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Veterinary antibacterial agent
Used in treatment of respiratory disease
Description
Isomers
Salt Data
Mesylate
Pharmacology Properties
Mechanism of Action
DNA gyrase and topoisomerase IV inhibitor
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• McGuirk, P.R. et al., J. Med. Chem., 1992, 35, 611, (synth, sar)
• Giles, C.J. et al., J. Vet. Pharmacol. Ther., 1991, 14, 400, (activity, pharmacokinet)
• Eur. Pat., 1989, Pfizer, 342 849; CA, 113, 6177m, (synth)
• Schneider, R.P. et al., Biol. Mass. Spectrom., 1993, 22, 595, (hplc-ms)