Substance

ID:449122

Names and Identifiers
Synonyms
BudesonideRhinocortEntocortPreferidPulmicortBudesonSpirocortOlfexPrederidInflammideLisoflamPulmaxanBudamaxDemotestNohalon
IUPAC name
(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
IUPAC Traditional name
(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
Registration numbers
CAS Number
51333-22-3
Properties
Pharmacology Properties
Mechanism of Action
Glucocorticoid steroid
Product Information
Application(s)
Used for the management of asthma, non-infectious rhinitis and for treatment of inflammatory bowel disease
Description
Stereoisomers 1:1
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 1034
• Spencer, C.M. et al., Drugs, 1995, 50, 854, (rev, pharmacol)
• Hvizdos, K.M. et al., Drugs, 2000, 60, 1141-1178, (rev)
• Clissold, S.P. et al., Drugs, 1984, 28, 485; 1992, 44, 375, (rev)
• Albertsson, J. et al., Acta Cryst. B, 1978, 34, 3027-3036, (cryst struct)
• Brattsand, R. et al., J. Steroid Biochem., 1982, 16, 779, (pharmacol)
• Thalen, A. et al., Acta Pharm. Suec., 1984, 21, 109; 145; 1987, 24, 97, (synth, pmr)
• Gauvreau, G.M. et al., Am. J. Resp. Crit. Care Med., 1996, 154, 1267, (pharmacol)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, BOM520
• McGavin, J.R. et al., Drugs, 2001, 61, 71-78, (rev)
• Wikby, A. et al., J. Chromatogr., 1978, 157, 65
• Thalen, A. et al., Arzneim.-Forsch., 1979, 29, 1687, (synth, pharmacol)
• Ryrfeldt, A. et al., Biochem. Pharmacol., 1989, 38, 17-22, (pharmacol)
• Korn, S.H. et al., Am. J. Resp. Crit. Care Med., 1997, 155, 1117, (pharmacol)
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