Substance
ID:449115
Names and Identifiers
IUPAC name
N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}oxolane-2-carboxamide
Synonyms
AlfotenZatralAlfuzosinMittoralUrion
IUPAC Traditional name
N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}oxolane-2-carboxamide
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Used in the treatment of benign prostatic hypertrophy
Antihypertensive agent
Pharmacology Properties
Mechanism of Action
alpha 1-Adrenoceptor antagonist
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Allen, J., J. Labelled Compd. Radiopharm., 1983, 20, 1283, (synth)
• Rouchouse, A. et al., J. Chromatogr., 1990, 506, 601, (hplc, enantiomers)
• U.S. Pat., 1982, Synthelabo, 4 315 007; CA, 96, 162737e, (synth)
• Scott, M.G. et al., Eur. J. Clin. Pharmacol., 1989, 37, 53, (pharmacokinet)
• Lefevre-Borg, F. et al., Br. J. Pharmacol., 1993, 109, 1282, (pharmacol)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 342
• Wilde, M.I. et al., Drugs, 1993, 45, 410, (rev)