Substance
ID:40
Names and Identifiers
Synonyms
DGLA8,11,14-Eicosatrienoic Acidcis-8,11,14-Eicosatrienoic acidgamma-Homolinolenic acid(8E,11E,14E)-8,11,14-Icosatrienoic acid(Z,Z,Z)-8,11,14-Eicosatrienoic acidDihomo-gamma-linolenic acidHomo-gamma-linolenic acid
Brand Name
Tona-lean 1000 CLA (Action Labs) Star GLA (GNC)
IUPAC name
(8Z,11Z,14Z)-icosa-8,11,14-trienoic acid
IUPAC Traditional name
gamma-homolinolenic acid
Properties
Physical Property
Hydrophobicity(logP)
6.8
Molecule Details
Drug Groups
approved; nutraceutical
Description
A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5. [PubChem]
Indication
For nutritional supplementation, also for treating dietary shortage or imbalance
Pharmacology
Dihomo gamma-linolenic acid or DHLA is an n-6 (omega-6) polyunsaturated fatty acid. It is comprised of 20 carbon atoms and three double bonds. DHLA is a byproduct of the 18 carbon gamma-linolenic acid (GLA). DHLA is then converted into prostaglandin E1 (PGE1). PGE1 inhibits platelet aggregation and also exerts a vasodilatory effect.
Affected Organisms
Humans and other mammals
External Links
Molecular Spectra
No Data Available
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References
No Data Available
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