Substance
ID:399313
Names and Identifiers
IUPAC name
1,2-benzoxazol-3-ylmethanesulfonamide
Synonyms
ZonisamideZonegranAleviatinExcegranPD 1108431,2-Benzisoxazole-3-methanesulfonamideAD 8103-(Sulfamoylmethyl)-1,2-benzisoxazole
IUPAC Traditional name
zonisamide
Registration numbers
CAS Number
Properties
Physical Property
Solubility
DMSO
Ethyl Acetate
Ethanol
Methanol
Melting Point
160-163°C
Apperance
White to Off-White Solid
Product Information
Certificate of Analysis
Safety Information
Storage Condition
Refrigerator
MSDS Link
Molecule Details
Sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Heterocyclic methanesulfonide with anticonvulsant properties. The compound is under investigation for potent
Molecular Spectra
No Data Available
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References
• Hammond, E.J., et al.: Gen. Pharmacol., 18, 303 (1980)
• Sorkin, E.M., et al.: Drugs, 45, 760 (1980)
• Masuda, Y., et al.: Arzneim.-Forsch., 30, 477 (1980)
• Schmidt, D., et al.: Epilepsy Res., 15, 67 (1980)