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Substance
ID:399238
Structure
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Functional Group
Text
ID:431
Zafirlukast
Toronto Research Chemicals
ID: Z125000
Names and Identifiers
Synonyms
Zafirlukast
[3-[[2-Methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]carbamic Acid Cyclopentyl Ester
ICI-2204219
Accolate
Vanticon
IUPAC name
cyclopentyl N-[3-({2-methoxy-4-[(2-methylbenzenesulfonyl)carbamoyl]phenyl}methyl)-1-methyl-1H-indol-5-yl]carbamate
IUPAC Traditional name
zafirlukast
Registration numbers
CAS Number
107753-78-6
Properties
Product Information
Certificate of Analysis
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Physical Property
Solubility
Chlorloform
Melting Point
190-193°C
Apperance
Pale Pink Solid
Safety Information
Storage Condition
Refrigerator
MSDS Link
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Molecule Details
A potent, selective and orally active cysteinyl leukotriene type 1 receptor antagonist. Used as an antiasthmatic.
Molecular Spectra
No Data Available
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References
•
Findlay, S.R., et al.: J. Allergy Clin. Immunol., 89, 1040 (1990)
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Dunn, C.J., Drugs, 61, 285 (1990)
•
Krell, R.D., et al.: Am. Rev. Respir. Dis., 141, 978 (1990)
•
Matassa, V.G., et al.: J. Med. Chem., 33, 1781 (1990)
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