Substance
ID:399117
Names and Identifiers
IUPAC Traditional name
rofecoxib
IUPAC name
4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one
Synonyms
MK 966rofecoxibVioxxRhuma-cure4-[4-(Methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone3-(4-Methanesulfonylphenyl)-2-phenyl-2-buten-4-olide3-Phenyl-4-[4-(Methylsulfonyl)phenyl]-2(5H)-furanoneMK 0966
Registration numbers
CAS Number
Properties
Physical Property
Solubility
Chloroform
Dimethyl formamide
DMSO
Apperance
Off-White Solid
Melting Point
207-209°C
Product Information
Certificate of Analysis
Safety Information
MSDS Link
Storage Condition
Refrigerator
Molecule Details
A selective cyclooxygenase-2 (COX-2) inhibitor. Use as an anti-inflammatory, analgesic.
Molecular Spectra
No Data Available
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References
• Langman, M.J., et al.: J. Am. Med. Assoc., 282, 1929 (1999)
• Catalla-Lawson, F., et al.: J. Pharmacol. Exp. Ther., 289, 735 (1999)
• Ehrich, E.W., et al.: Clin. Pharmacol. Ther., 65, 336 (1999)