Substance
ID:399016
Names and Identifiers
IUPAC Traditional name
2-(2,4-difluorophenyl)-6-[1-(2,6-difluorophenyl)carbamoylamino]pyridine-3-carboxamide
IUPAC name
2-(2,4-difluorophenyl)-6-[1-(2,6-difluorophenyl)carbamoylamino]pyridine-3-carboxamide
Synonyms
VX-7026-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide
Registration numbers
CAS Number
Properties
Product Information
Certificate of Analysis
Safety Information
MSDS Link
Molecule Details
VX-702 is a p38 mitogen-activated protein kinase (MAPK) inhibitor. VX-702 had no effect on platelet aggregation induced by any of the p38 MAPK agonists. VX-702 has potential use in the treatment of inflammation, rheumatoid arthritis and cardiovascular dis
Molecular Spectra
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References
• Kuliopulos, A. et al.: Thromb. Haemost., 92, 1387 (2004)
• Ding, C.: Curr. Opin. Invest. Drug, 7, 1020 (2004)
• Cohen, S. et al.: Curr. Opin. Rheumatol., 22, 330 (2004)