Substance
ID:398810
Names and Identifiers
Synonyms
S-Trityl-L-cysteineS-Triphenylmethyl-L-cysteine(2R)-2-Amino-3-[(triphenylmethyl)thio]propanoic AcidS-Trityl-(R)-cysteineS-TritylcysteineTritylthioalanine3-Tritylthio-L-alanineNSC 83265S-(Triphenylmethyl)-L-cysteine
IUPAC Traditional name
(2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoic acid
IUPAC name
(2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoic acid
Registration numbers
CAS Number
Properties
Physical Property
Solubility
DMSO
Apperance
White Solid
Melting Point
>160°C (dec.)
Safety Information
Storage Condition
-20°C Freezer
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
A protected cysteine for peptide synthesis. S-Trityl-L-cysteine (STLC) is a tight-binding inhibitor of Eg5 that prevents mitotic progression. It has proven antitumor activity as shown in the NCI 60 tumor cell line screen.
Molecular Spectra
No Data Available
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References
• Zhu, C., et al.: Mol. Biol. Cell, 16, 3187 (2004)
• Sakowicz, R., et al.: Cancer Res., 64, 3276 (2004)
• Brier, S., et al.: Biochemistry, 43, 13072 (2004)