Substance

ID:397459

1,2,3,4-Tetrahydro-β-carboline

Names and Identifiers
IUPAC Traditional name
tryptoline
IUPAC name
1H,2H,3H,4H,9H-pyrido[3,4-b]indole
Synonyms
NoreleagnineTryptoline1,2,3,4-TetrahydronorharmanTetrahydronorharman, THBC1,2,3,4-Tetrahydro-β-carboline1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole
Registration numbers
CAS Number
Properties
Physical Property
Apperance
Tan Solid
Solubility
10mg/mL in 1N Ammonium Hydroxide in Methanol
DMSO
Melting Point
206-208°C
Safety Information
MSDS Link
Storage Condition
Refrigerator
Product Information
Certificate of Analysis
Molecule Details
A mitotic kinesin inhibitor as novel anti-cancer agent. Used in the study of neurodegenerative diseases.
Molecular Spectra
No Data Available
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References
• Lee, Y., et al.: Biochem. J., 360, 549 (1994)
• Sharp, D., et al.: Nature, 407, 41 (1994)
• Brown, K., et al.: J. Cell Biol., 125, 1303 (1994)
• Sueishi, M., et al.: J. Biol. Chem., 275, 28888 (1994)