Substance
ID:397274
Names and Identifiers
IUPAC Traditional name
terbinafine hydrochloride
IUPAC name
[(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)(naphthalen-1-ylmethyl)amine hydrochloride
Synonyms
Terbinafine hydrochlorideLamisilMuzonalTerbinaBramizilTerbineN-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-N-methyl-1-naphthalenemethanaminetrans-N-Methyl-N-(1-naphthylmethyl)-6,6-dimethylhept-2-en-4-ynyl-1-amineBramazil
Registration numbers
CAS Number
Properties
Safety Information
MSDS Link
Storage Condition
-20°C Freezer
Physical Property
Solubility
Methanol
Melting Point
195-198°C
Apperance
White Solid
Product Information
Certificate of Analysis
Molecule Details
An orally active, antimycotic allylamine related to Naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Antifungal.
Molecular Spectra
No Data Available
Click here to submit data
References
• Petranyi, G., et al.: Science, 224, 1239 (1984)
• Evans, E.G.V., et al.: Br. Med. J., 318, 1031 (1984)
• Ryder, N.S., et al.: Antimicrob. Agents Chemother., 27, 252 (1984)