Substance
ID:397253
Names and Identifiers
IUPAC name
({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid
IUPAC Traditional name
tenofovir
Synonyms
Tenofovir[[(1R)-2(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid(R)-9-(2-Phosphonomethoxypropyl)adenine(R)-PMPAGS-1278
Registration numbers
CAS Number
Properties
Physical Property
Apperance
White to Off-White Solid
Melting Point
280-282°C
Solubility
Warm DMSO
Warm Water
Product Information
Certificate of Analysis
Safety Information
MSDS Link
Storage Condition
-20°C Freezer
Molecule Details
Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.
Molecular Spectra
No Data Available
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References
• Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997)
• Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (1997)
• Wyles, D., et al.: Clin Infect. Dis., 40, 174 (1997)
• Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (1997)