Substance
ID:397168
Names and Identifiers
IUPAC name
N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride
IUPAC Traditional name
erlotinib hydrochloride
Synonyms
[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4yl]-(3-ethynyl-phenyl)-amineTarceva (Erlotinib Hydrochloride)N-(3-Ethynylphenyl)-6,7-bis-(2-methoxyethoxy)-quinazolin-4-amineErlotinib Hydrochloride
Registration numbers
CAS Number
Properties
Physical Property
Apperance
Off-White Solid
Solubility
Acetic Acid
Dimethyl Sulfoxide
Methanol (Sparingly)
Dimethylformamide
Melting Point
223-225°C
Safety Information
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
Selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor. Antineoplastic.
Molecular Spectra
No Data Available
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References
• Perez-Soler, R., et al.: J. Clin. Oncol., 22, 3238 (1997)
• Moyer, J.D., et al.: Cancer Res., 57, 4838 (1997)
• Hidalgo, M., et al.: J. Clin. Oncol., 19, 3267 (1997)
• Blackhall, F.H., et al.: Expert Opin. Pharmacother., 6, 995 (1997)