Substance
ID:397113
Names and Identifiers
Synonyms
TridolgosirSwainsonine8α,β-Octahydroindolizidine-1α,2α,8β-triol(-)-Swainsonine
IUPAC name
(1S,2R,8R,8aR)-octahydroindolizine-1,2,8-triol
IUPAC Traditional name
swainsonine
Registration numbers
CAS Number
Properties
Product Information
Certificate of Analysis
Physical Property
Melting Point
>125°C (dec.)
Solubility
Water
Methanol
DMSO
Apperance
White to Off-White Solid
Safety Information
MSDS Link
Storage Condition
-20°C Freezer
Molecule Details
Swainsonine is a plant alkaloid derived from Swainsona canescens (a leguminous plant). It is a reversible, active-site directed inhibitor of a-mannosidase at concentrations of 5-10mM. At acid pH, swainsonine resembles an intermediate in the hydrolysis of
Molecular Spectra
No Data Available
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References
• Methods Enzymol., 98, 135 (1983)
• J. Biol. Chem., 258, 7578-7585 (1983)
• Mol. Cell. Biol., 5, 3467-3475 (1983)
• EMBO Journal, 3, 551-556 (1983)
• Bonay, P., & Fresno, M.: Glycobiology, 9(1983)
• Melanoma Res., 1, 43 (1983)
• 423-4
• Int. J. Cancer, 44, 685 (1983)