Substance
ID:397038
Names and Identifiers
IUPAC Traditional name
tamoxifen
IUPAC name
(2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine
Synonyms
TamoxifenTrans-Tamoxifen(Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamineTamoxifenICI 47699NovaldexZ-TamoxifenMammaton
Registration numbers
CAS Number
Properties
Safety Information
MSDS Link
Storage Condition
Amber Vial, -20°C Freezer
Product Information
Certificate of Analysis
Physical Property
Solubility
Dichloromethane
Melting Point
92-94°C
Apperance
White Crystalline Solid
Molecule Details
Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2
Molecular Spectra
No Data Available
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References
• Sutherland, R., et al.: Nature, 267, 434 (1977)
• Love, R., et al.: J. Clin. Oncol., 20 2559 (1977)
• Lerner, L., et al.: Cancer Res., 50, 4177 (1977)