Substance
ID:396791
Names and Identifiers
IUPAC name
4-(4-{2-[(1S)-3,4-dihydro-1H-2-benzopyran-1-yl]ethyl}piperazin-1-yl)benzene-1-sulfonamide
Synonyms
Sonepiprazole4-[4-[2-[(1S)-3,4-Dihydro-1H-2-benzopyran-1-yl]ethyl]-1-piperazinyl]benzenesulfonamidePF-05191680PNU 101387(S)-4-[4-[2-(3,4-Dihydro-1H-2-benzopyran-1-yl)ethyl]-1-piperazinyl]benzenesulfonamideU 101387
IUPAC Traditional name
sonepiprazole
Registration numbers
CAS Number
Properties
Safety Information
MSDS Link
Storage Condition
Refrigerator
Product Information
Certificate of Analysis
Physical Property
Apperance
Off-White Solid
Solubility
DMSO
Melting Point
183-185°C
Molecule Details
A selective D4 dopamine antagonist that exhibits low affinity at other monoamine receptors (Ki > 2000 nM). Induces c-fos gene expression in medial prefrontal cortex in a similar manner to Clozapine (C587500).
Molecular Spectra
No Data Available
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References
• Rubinstein, M. et al.: J. Neurosci., 21, 3756 (1996)
• Marona-Lewicka, D. et al.: Behav. Pharmacol., 20, 114 (1996)
• Merchant, K.M. et al.: J. Pharm. Exp. Ther., 279, 1392 (1996)