Substance
ID:396745
Names and Identifiers
Synonyms
SN-3810-Hydroxy-7-ethylcamptothecin(4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione7-Ethyl-10-hydroxycamptothecinSN 38 Lactone
IUPAC Traditional name
(19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
IUPAC name
(19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
Registration numbers
CAS Number
Properties
Physical Property
Apperance
Light-Yellow Solid
Solubility
DMSO
Melting Point
218-221°C dec.
Safety Information
Storage Condition
-20°C Freezer
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
A metabolite of Irinotecan, a DNA topoisomerase inhibitor.
Molecular Spectra
No Data Available
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References
• Ashley, G., et al.: J. Antibiot., 57, 224 (2000)
• Teiber, J., et al.: Biochem. Pharmacol., 66, 887 (2000)
• Billecke, S., et al.: Drug Metab. Dispos., 28, 1335 (2000)