Substance
ID:396450
Names and Identifiers
IUPAC name
3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
Synonyms
DaxasRoflumilastB 9302-107BY 217BYK 208693-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide
IUPAC Traditional name
roflumilast
Registration numbers
CAS Number
Properties
Physical Property
Solubility
Chlorform
DMSO
Melting Point
154-158°C
Apperance
White to Off-White Solid
Safety Information
MSDS Link
Storage Condition
-20°C Freezer
Product Information
Certificate of Analysis
Molecule Details
Selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease.
Molecular Spectra
No Data Available
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References
• Timmer, W., et al.: J. Clin. Pharmacol., 42, 297 (2001)
• Schmidt, B.M.W., et al.: J. Allergy Clin. Immunol., 108, 530 (2001)
• Rabe, K.F., et al.: Lancet, 366, 563 (2001)
• Hatzelmann, A., et al.: J. Pharmacol. Exp. Ther., 297, 267 (2001)