Substance
ID:396395
Names and Identifiers
IUPAC Traditional name
rilpivirine
IUPAC name
4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile
Synonyms
RilpivirineR 2784744-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrileTMC 278
Registration numbers
CAS Number
Properties
Physical Property
Apperance
N/ABright Yellow Solid
Solubility
DMSO
Melting Point
241-243°C
Safety Information
Storage Condition
Refrigerator
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
A novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.
Molecular Spectra
No Data Available
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References
• Sun, et al.: J. Med. Chem., 41, 4648 (1998)
• Kashiwada, et al.: Bioorg. Med. Chem. Lett., 11, 183 (1998)