Substance

ID:395972

5-Pyrimidineboronic Acid Pinacol Ester

Names and Identifiers
IUPAC name
5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
IUPAC Traditional name
5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
Synonyms
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine5-Pyrimidineboronic Acid Pinacol EsterPyrimidyl-5-boronic acid pinacolate
Registration numbers
CAS Number
Properties
Product Information
Certificate of Analysis
Safety Information
MSDS Link
Molecule Details
2-Methoxyphenylborornic Acid Pinacol Ester is used in the preparation of indole derivatives as selective inhibitors of all three members of the Pim kinase family. It is also used to prepare inhibitors of TGF-β1 and activin A signalling.
Molecular Spectra
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References
• Nishiguchi, G.A. et al.: Bioorg. Med. Chem. Lett., 21, 6366 (2011)
• Ciayadi, R. et al.: Bioorg. Med. Chem. Lett., 21, 5642 (2011)