Substance
ID:395969
Names and Identifiers
Synonyms
DaraprimPyrimethamineMalocidePirimecidan5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamineNSC 3061RP 4753Pirimetmin2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidineKhloridinChloridinChloridine
IUPAC Traditional name
pyrimethamine
IUPAC name
5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
Registration numbers
CAS Number
Properties
Safety Information
MSDS Link
Storage Condition
-20°C Freezer
Product Information
Certificate of Analysis
Physical Property
Solubility
Ethanol (hot)
DMSO
Melting Point
233-234°C
Apperance
White Solid
Molecule Details
Dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial.
Molecular Spectra
No Data Available
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References
• Leport, C., et al.: Am. J. Med., 84, 94 (1983)
• McIntosh, H.M., et al.: Ann. Trop. Med., Parasitol., 93, 265 (1983)
• Plowe, C.V., et al.: Br. Med. J., 328, 545 (1983)
• Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 463 (1983)