Substance
ID:395442
Names and Identifiers
IUPAC name
(2E)-3-{2-butyl-1-[2-(diethylamino)ethyl]-1H-1,3-benzodiazol-5-yl}-N-hydroxyprop-2-enamide
IUPAC Traditional name
(2E)-3-{2-butyl-1-[2-(diethylamino)ethyl]-1,3-benzodiazol-5-yl}-N-hydroxyprop-2-enamide
Synonyms
SB939(2E)-3-[2-Butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl]-N-hydroxy-2-propenamide(2E)-3-[2-Butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl]-N-hydroxyacrylamide(E)-3-[2-Butyl-1-(2-diethylaminoethyl)-1H-benzimidazol-5-yl]-N-hydroxy-2-propenamidePracinostatKaempferol 3-O-β-D-(6-E-p-Coumaroylglucoside)SB 939
Registration numbers
CAS Number
Properties
Safety Information
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
Pracinostat is a potent and orally active histone deacetylase (HDAC) inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer. The selectivity of Pracinostat for tumor tissues makes it a promising therapeutic candidate for use
Molecular Spectra
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References
• Novotny-Diermayr, V. et al.: Mol. Cancer Therap., 9, 642 (2010)
• Razak, A.R.A. et al.: Br. J. Cancer, 104, 756 (2010)
• Novotny-Diermayr, V. et al.: Mol. Cancer Therap., 10, 1207 (2010)