Substance
ID:394676
Names and Identifiers
Synonyms
4,4'-[1,5-Pentanediylbis(oxy)]bis-benzenecarboximidamidePentamidine4,4'-Diamidino-.alpha.,.omega.-diphenoxypentaneNSC 9921MP 601205p,p'-(Pentamethylenedioxy)dibenzamidine
IUPAC name
4-{[5-(4-carbamimidoylphenoxy)pentyl]oxy}benzene-1-carboximidamide
IUPAC Traditional name
pentamidine
Registration numbers
CAS Number
Properties
Safety Information
MSDS Link
Storage Condition
-20°C Freezer, Under Inert Atmosphere
Product Information
Certificate of Analysis
Physical Property
Melting Point
198-200°C (dec.)
Solubility
DMSO
Methanol (Sparingly)
Apperance
Off-White Solid
Molecule Details
Has been widely used as a drug to treat protozoal diseases, such as malaria, amoebic dysentery and trypanosomiasis. It has also been shown to be effective for both prophylaxis of pneumocystic carinii pneumonia (PCC).
Molecular Spectra
No Data Available
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References
• Debs, R.J., et al.: Antimicrob. Agents Chemother., 31, 37 (1987)
• Hesk, D., et al.: J. Lab. Comp. Radiopharm., 28, 11, 1309 (1990)
• Walzer, P.D., et al.: Antimicrob. Agents Chemother., 32, 896 (1987)
• Goa, K.L., et al.: Drugs, 33, 242 (1987)