Substance
ID:393930
Names and Identifiers
IUPAC Traditional name
sodium 7-{[(2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyloxan-2-yl]oxy}-3-[4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamido]-8-methyl-2-oxochromen-4-olate
IUPAC name
sodium 7-{[(2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyloxan-2-yl]oxy}-3-[4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamido]-8-methyl-2-oxo-2H-chromen-4-olate
Synonyms
Albamycin SodiumCathomycin Sodium LyovacN-[7-[[3-O-(Aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-α-L-lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-4-hydroxy-3-(3-methyl-2-butenyl)benzamide monosodium saltCathomycin SodiumNSC 2382Novobiocin Sodium SaltVulcamycin
Registration numbers
CAS Number
Properties
Product Information
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Safety Information
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Molecule Details
Novobiocin is an antibiotic that acts as an inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. Studies show that Novobiocin is also an inhibitor of retrovirus RNA-dependent DNA-polymerase. Novobiocin is used in the production of positivel
Molecular Spectra
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References
• Sumiyoshi, Y. et al.: J. Gen. Virol., 64, 2329 (1980)
• Lockshon, G. et al.: Nucleic Acids Res., 11, 2999 (1980)
• Cozarelli, N.R.: Science, 207, 953 (1980)