Substance
ID:393061
Names and Identifiers
Synonyms
BI-RG 587ViramuneNevirapine11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2’,3’-e][1,4]diazepin-6-oneNSC 641530Nevarapine
IUPAC Traditional name
nevirapine
IUPAC name
2-cyclopropyl-7-methyl-2,4,9,15-tetraazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one
Registration numbers
CAS Number
Properties
Physical Property
Solubility
Chloroform
Methanol
Apperance
Off-white to Pale Yellow Solid
Melting Point
247-249°C
Product Information
Certificate of Analysis
Safety Information
MSDS Link
Storage Condition
-20°C Freezer
Molecule Details
A potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Antiviral.
Molecular Spectra
No Data Available
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References
• Hargrave, K.D., et al.: J. Med. Chem., 34, 2231 (1991)
• Guay, L.A., et al.: Lancet, 354, 795 (1991)
• Cheeseman, S.H., et al.: Antimicrob. Agents Chemother., 37, 178 (1991)