Substance
ID:392968
Names and Identifiers
IUPAC Traditional name
nilotinib
Synonyms
AMN107NilotinibTasigna4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide
IUPAC name
4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide
Registration numbers
CAS Number
Properties
Physical Property
Solubility
Chloroform
DMSO
Apperance
Off-White to Pale Yellow Solid
Melting Point
234-236°C
Safety Information
Storage Condition
-20°C Freezer
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
Nilotinib (AMN1O7) might be useful in treatment of chronic myelogenous leukemia.
Molecular Spectra
No Data Available
Click here to submit data
References
• Gleixner, K., et al.: Blood, 107, 752 (2002)
• Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002)
• Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2002)
• Nicolini, F., et al.: Leukemia, 20, 1061 (2002)