Substance

ID:392137

Methyl-(5-[2-thienylcarbonyl]-1H-benzimidazol-2yl)carbamate

Names and Identifiers
IUPAC name
methyl N-[6-(thiophene-2-carbonyl)-1H-1,3-benzodiazol-2-yl]carbamate
Synonyms
NocodazoleR 17934OncodazoleN-[5-(2-Thenoyl)-2-benzimidazolyl]carbamic Acid Methyl EsterMethyl-(5-[2-thienylcarbonyl]-1H-benzimidazol-2yl)carbamateNSC 238159N-[6-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]carbamic Acid Methyl Ester
IUPAC Traditional name
nocodazole
Registration numbers
CAS Number
Properties
Physical Property
Apperance
Light Tan to Brown Solid
Melting Point
>280°C (dec.)
Solubility
DMSO
Safety Information
MSDS Link
Storage Condition
-20°C Freezer
Product Information
Certificate of Analysis
Molecule Details
A synthetic chemotherapeutic agent with antineoplastic, antifungal and anthelmintic activities. Microtubule inhibitor; inhibits mitosis.
Molecular Spectra
No Data Available
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References
• Massa, S., et al.: J. Het. Chem., 27, 1131 (1985)
• Lacey., E., et al.: Biochem. Pharmacol., 34, 3603 (1985)
• Rennison et al.: J. Cell. Sci. , 102, 239 (1985)
• Vasquez et al. Mol. Biol. Cell, 8, 973
• Lacey., E., et al.: Biochem. Pharmacol., 34, 1073 (1985)