Substance
ID:390402
Names and Identifiers
IUPAC Traditional name
2-methoxyestradiol
Synonyms
2-Hydroxyestradiol 2-methyl etherNSC 659853Panzem(17β)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol2-Methoxy 17β-Estradiol2-Methoxyestra-1,3,5(10)-triene-3,17β-diol2-Methoxyestradiol
IUPAC name
(1S,10R,11S,14S,15S)-4-methoxy-15-methyltetracyclo[8.7.0.02,7.011,15]heptadeca-2(7),3,5-triene-5,14-diol
Registration numbers
CAS Number
Properties
Safety Information
MSDS Link
Storage Condition
-20°C Freezer
Physical Property
Solubility
Chloroform
Methanol
Apperance
Off-White Solid
Melting Point
188-190°C
Product Information
Certificate of Analysis
Molecule Details
2-Methoxy 17β-Estradiol is a natural metabolite of 17β-Estradiol which is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. 2-Methoxy 17β-Estradiol binds to the colchicine binding site of tubulin, and has been suggested to func
Molecular Spectra
No Data Available
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References
• Cushman, M., et al.: J. Med. Chem., 38, 2041 (1995)
• D’Amato, R.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 3964 (1995)
• Forsis, T., et al.: Nature, 368, 237 (1994)