Substance
ID:390272
Names and Identifiers
Synonyms
TrexallRheumatrexAntifolanMexateMethotrexateMethylaminopterinNSC 740R 9985N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic Acid4-Amino-N10-methylpteroylglutamic AcidEmtexateEMT 25299L-Metatrexan4-Amino-N10-methylfolic AcidCL 14377LedertrexateMTX(+)-Amethopterin
IUPAC Traditional name
methotrexate
IUPAC name
(2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid
Registration numbers
CAS Number
Properties
Physical Property
Apperance
Yellow Solid
Solubility
DMSO
Melting Point
>188°C (dec.)
Product Information
Certificate of Analysis
Safety Information
Molecule Details
A Folic acid antagonist. Used as a antineoplastic and antirheumatic.
Molecular Spectra
No Data Available
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References
• Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1958)
• Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958)