Substance
ID:390263
Names and Identifiers
IUPAC Traditional name
L-methionine sulfoximine
IUPAC name
(2S)-2-amino-4-[imino(methyl)oxo-λ6-sulfanyl]butanoic acid
Synonyms
L-S-[3-Amino-3-carboxypropyl]-S-methyl-[R,S]-sulfoximine(2S)-2-Amino-4-(S-methylsulfonimidoyl)butanoic AcidL-Methionine [R,S]-Sulfoximine
Registration numbers
CAS Number
Properties
Physical Property
Melting Point
>210°C (dec.)
Apperance
White Solid
Solubility
Water
Product Information
Certificate of Analysis
Safety Information
Molecule Details
Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM).Methionine sulfoximine is also a toxic by
Molecular Spectra
No Data Available
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References
• Griffith, O.W., and Meister, A.: J. Biol. Chem. 254, 7558 (1979)
• Willard-Mack, C.L., et al: Neuroscience, 71, 2, 589 (1996)