Substance
ID:389516
Names and Identifiers
IUPAC name
3-[4-(3-amino-1H-indazol-4-yl)phenyl]-1-(2-fluoro-5-methylphenyl)urea
IUPAC Traditional name
3-[4-(3-amino-1H-indazol-4-yl)phenyl]-1-(2-fluoro-5-methylphenyl)urea
Synonyms
N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)ureaABT 869Linifanib
Registration numbers
CAS Number
Properties
Physical Property
Apperance
Beige Solid
Solubility
Methanol
DMSO
Melting Point
180-183°C (dec.)
Product Information
Certificate of Analysis
Safety Information
MSDS Link
Storage Condition
-20°C Freezer
Molecule Details
Linifanib (ABT 869) is an oral tyrosine kinase inhibitor with antineoplasic activity. As a dual inhibitor, Linifanib, is being tested on several different cancers.
Molecular Spectra
No Data Available
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References
• Cheng, A., et al.: J. Med. Chem., 53, 4502 (2010)
• Haddley, K., et al.: Drugs of the Future, 35, 106 (2010)