Substance
ID:389396
Names and Identifiers
IUPAC name
2,2-dimethyl-2H,3H,4H,5H,6H-naphtho[1,2-b]pyran-5,6-dione
IUPAC Traditional name
β-lapachone
Synonyms
3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dioneNSC 26326SL 11001ARQ 501NSC 629749β-Lapachone
Registration numbers
CAS Number
Properties
Safety Information
Storage Condition
-20°C Freezer
MSDS Link
Product Information
Certificate of Analysis
Physical Property
Apperance
Orange Solid
Melting Point
>110°C (dec.)
Solubility
Chloroform
Molecule Details
β-Lapachone is a naturally occurring quinone obtained from the bark of the lapacho tree (Tabebuia avellanedae) with cancer chemopreventive properties. Induces apoptosis in HL-60 and human prostate cancer cells.
Molecular Spectra
No Data Available
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References
• Stuart, K., et al.: J. Clin. Invest., 118, 1301 (2006)
• Renslo, A., et al.: Nat. Chem. Biol., 2, 701 (2006)
• Martin, R., et al.: Science, 25, 1680 (2006)
• Hopkins, A., et al.: Nat. Chem. Biol., 4, 682 (2006)