Substance
ID:389339
Names and Identifiers
IUPAC Traditional name
lamivudine
IUPAC name
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one
Synonyms
3TCHeptovirZeffixLamivudineHeptodinLamivirβ-L-2',3'-Dideoxy-3'-thiacytidineβ-L-3'-Thia-2',3'-dideoxycytidine4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone(2R-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone(-)-2'-Deoxy-3'-thiacytidineEpivir HBVHepitecL-SddCVirolam(-)-BCH 189
Registration numbers
CAS Number
Properties
Physical Property
Apperance
White Solid
Melting Point
171-173°C
Solubility
Methanol
Sparingly Sol. in Ethanol
Water
Product Information
Certificate of Analysis
Safety Information
Storage Condition
Refrigerator
MSDS Link
Molecule Details
Lamivudine is a potent nucleoside reverse transcriptase inhibitor. Antiviral. Lamivudine has been used for treatment of chronic hepatitis B.
Molecular Spectra
No Data Available
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References
• Perry, C.M., et al.: Drugs, 53, 657 (1944)
• Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944)
• Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1944)