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Substance
ID:388633
Structure
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Functional Group
Text
ID:213
Indomethacin
Toronto Research Chemicals
ID: I641000
Names and Identifiers
IUPAC name
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
Synonyms
Indomethacin
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid
IUPAC Traditional name
indomethacin
Registration numbers
CAS Number
53-86-1
Properties
Safety Information
Storage Condition
-20°C Freezer
MSDS Link
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Physical Property
Melting Point
155°C Polymorphism
Solubility
Ether
Ethanol
Acetone
Apperance
Off-White Solid
Product Information
Certificate of Analysis
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Molecule Details
Inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.
Molecular Spectra
No Data Available
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References
•
Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984)
•
Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)
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